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NAC Virtual RoadshowIn this Issue March 2004

 

IPCRG 2nd World Conference Review

SARS war - defending the frontline

'Flu Season Looms 

Virtual Roadshow - Children, asthma and the real world! 

The TSANZ 2004 Annual Scientific Meeting 

Conference Diary 2004

IPCRG 2nd World Conference Review

Following a few weeks to reflect on the IPCRG 2nd World Conference in Melbourne last month, for those of you who had the opportunity to attend you would no doubt agree it was a stimulating meeting.

The calibre of presentation and excellent level of interest in all presentations certainly seemed to fulfil Dr H John Fardy's expectation of addressing the challenges of learning, sharing, experiencing and enjoying all aspects of the conference.

Keynote 6

Associate Professor P Y Cheong, from Singapore, gave an absorbing and comprehensive presentation about how SARS impacted on Singapore. With SARS spreading at the speed of a plane, Dr Cheong explained how the SARS virus came from a single hotel-room resident in Hong Kong and cost Singapore some $8 billion.

Temperature was the only defence and with the knowledge that the incubation period was 10 days, medical teams worked 10 days on and 10 days off.

Primary care doctors were really at the frontline of this emergency with some novel challenges. Many primary care facilities are in high rise buildings which poses unique problems when a suspected SARS patient was identified. Getting the patient out of the building without exposure to other building occupants required careful planning.

Four important lessons became apparent as the epidemic finally was contained.

Firstly, that in the SARS situation there was more than one frontline. Understanding how infectious disease can spread, who might be a carrier and the incubation period are crucial. The flow of hospital workers throughout the facility, whether or not they are medical personnel, was significant. Understanding that infection can spread beyond the hospital well before symptoms develop leaves all the community vulnerable.

Secondly, communication with the community had to be open and direct. The difficulty of isolation for suspect cases was exceeded only by the sadness of having to be nursed without human touch, particularly for those patients who did not survive. 

Thirdly, through the total defence measures instituted in Singapore with Ministry of Health and Primary Care working in concert, no doctor in Primary Care got SARS.

And, finally when there is something around like SARS, a case anywhere in the world is a threat everywhere.

Associate Professor Cheong's abstract follows.Top of page

SARS war - defending the frontline

IPCRG 2nd World Conference - MelbourneP Y Cheong Community Occupational & Family Medicine Dept, National University of Singapore

Purpose:

The Severe Acute Respiratory Syndrome (SARS) epidemic in Singapore began on 1st March 2003 and ended three months later with 238 persons infected, 42% of them healthcare workers (HCW) and 33 deaths. This paper chronicles the experience of setting up the rings of defence as the epidemic wore on.

Methods:

The strategy that evolved of detect, isolate and ring-fencing (DIR) the virus using 4 rings of defence against this hitherto unknown disease is described. The sources of this chronicle are from local and world-wide mass media and medical literature

Results:

The Border Defence

All local cases in the epidemic can be traced to just one of the 8 imported cases. The border is thus a defence ring. Thermal scanning and health declaration of passengers were implemented from April. A retrospective study however revealed that of about 443 thousands persons screened, 136 were sent for further screening but none was diagnosed as SARS. The enormous economic risk of even one in-bound SARS patient causing community spread is nevertheless justification enough.

The Hospital Defence.

The learning curve of defending the hospitals was steep. In Tan Tock Seng Hospital (TTSH) where the first patients were warded, universal Personal Protection Equipment (PPE) of N95 masks, gloves, gowns & goggles (M3G) plus barrier nursing in single patient isolation rooms were instituted once it was clear that SARS was very infectious to both HCW and patients and can be lethal. These measures and strong clinical leadership to maintain staff discipline and morale stopped all nocosomial transmission by 5th April. However, it was not known then that signs of SARS may be masked in immuno-compromised patients. A few such patients (with the virus but not considered SARS suspects) discharged from ‘TSH were later admitted to other hospitals forming clusters of cases. This lesson learnt led to swift global implementation of strict same hospital re-admission policy, home quarantine orders (HQO) for 10 days for all discharged patients, no visitor rule, and mandatory PPE, temperature monitoring and restricted movements of every HCW. SARS suspect patients were immediately transferred to the SARS hospital, TTSH by special ambulances.

The Community Defence.

Community defence initially emphasised knowledge of SARS and personal hygiene. A watershed event was the closure of a large wholesale food market on 20th April and deployment of the army to trace within 24 hours more than 2000 people for HQO. Three days later, the Prime Minister invoked a total defence doctrine involving personal responsibility encompassing every sector of society to ensure that ‘there are no holes in our ring-fence against SARS’. Community and civic organizations rallied.

Twice daily temperature taking was implemented at schools and workplaces to detect fever as an early sign of SARS and also as a mass psychological defence exercise. A Courage Fund for public donation and a mass public campaign to appreciate (and not ostracise) HCW boosted morale. Intense efforts were made to ensure that the SARS messages of DIR reached groups at risk of being uninformed for example elderly illiterates.

The Primary Care Defence.

The primary care defence ring had the arduous tasks of detecting suspect SARS from other common flu-like febrile illnesses for immediate isolation in TTSH. A SARS workgroup set up by the College of Family Physicians was crucial in translating Ministry of Health (MOH) directives into practical measures. Such advisories were disseminated by print, e-mails and web-casting. The community outbreak in the wholesale market created fear of wider community spread. Contact with suspect SARS patients and travel history can no longer be relied upon. Amongst other measures, a telephone hotline manned by doctors was thus set up on 7 May to clarify diagnostic, PPE and HQO difficulties.

Conclusions

The SARS virus spread by jet from Hong Kong incognito to Singapore and other affected countries. It spread to a few hospitals and into the community. This epidemic showed that erecting the four rings of defence to detect, isolate and ring-fence the virus, is crucial to rapidly contain outbreaks caused by SARS.

For more on IPCRG Program Highlights go to
IPCRG Melbourne 2004
(http://www.ipcrg-melbourne.org/news.htm#high)

'Flu Season Looms

Purposely, this article about influenza follows the Singapore SARS story. Fortunately to date in Australia there has not been a death involving SARS. However each year more people die from the 'flu and pneumonia than perish in traffic accidents. And it is not just the elderly either.

People at particular risk of severe complications from influenza include those with heart conditions, asthma and other lung conditions, diabetes, kidney problems, those with weakened immune systems, residents of nursing homes and other long-term care facilities, as well as anybody over the age of 65 years regardless of their health status.

Beyond those in immediate danger from 'flu are the people who care for, or are in close contact with, those at particular risk. Being in the position to continue to care is vital, so avoiding infection and the potential to pass it on is a necessity. If you are self-employed, a single parent, carer or person who cannot afford to take 10 days out with the 'flu, it is time to have your injection.

Useful Resources

Asthma & Influenza - the Facts 

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Virtual Roadshow - Children, asthma and the real world!

The National Asthma Council invites you to our second Virtual Roadshow on Wednesday 21st April 2004, from 7.30 – 8.30 pm (AEST).

The Virtual Roadshow is an online presentation with an interactive Q&A session, run directly from a computer via the Internet. CPD/CME/CPE points will be available for participation.

Dr Ron Tomlins, Chairman, National Asthma Council will facilitate presentations and discussions by three expert panellists:

  • Prof. Nicholas Glasgow
    Director, Australian Primary Care Health Research Institute,
    the Australian National University, Canberra

  • Dr Dominic Fitzgerald
    Paediatric respiratory and sleep physician
    Deputy Head of the Division of Academic and General Medicine at the Children’s Hospital
    Westmead, Sydney

  • Dr Amanda Barnard
    General Practitioner,
    Claremont, Western Australia
    Senior Lecturer, Department of General Practice,
    University of Western Australia

The panellists will discuss daily practice issues such as:

  • Types of medication pathways

  • The importance of lung function testing – case study

  • Adherence – the key driver for good asthma management

  • How it is done in general practice – case study

The panellists will answer your questions about paediatric asthma live, during and immediately after the Virtual Roadshow. For the next three days, the panellists will answer additional questions online, within 24 hours.

For more information go to

NAC Virtual Roadshow

Top of pageThe Thoracic Society of Australia and New Zealand 
2004 Annual Scientific Meeting 

The 2004 TSANZ scientific meeting was recently held in Sydney.  A selection of presentations concerning asthma with particular relevance to general practice were presented.

 

Brief Content

Converting Evidence to Practice – MDI & Spacer V’s Nebuliser

Vanessa McDonald1, Peter G Gibson1,2, Michael J Hensley1,2 and Jennifer Roberts2

1. Department of Respiratory and Sleep Medicine, John Hunter Hospital, NSW 2310 2. School of Medical Practice & Population Health, University of Newcastle, NSW 2308

Despite the the evidence to show that metered dose inhalers and spacers are as good as nebulisers, in practice at three local hospital only 30% of medical staff preferred them for acute asthma. This figure rose to 60% when MDI and inhaler was used for COPD.

Despite MDI and inhaler being best practice for asthma, knowledge and traditional practice are barriers to change.

Factors Associated With Asthma Practical knowledge.

Brett G Toelle BA1, Stewart M Dunn PhD MPH2, Guy B Marks PhD FRACP1.

1. Woolcock Institute of Medical Research, University of Sydney & 2. Department of Psychological Medicine, University of Sydney.

Use of hypothetical scenarios to test people 16 years or more, with doctor diagnosed asthma and prescribed daily preventer medication about practical knowledge of asthma.  People were scored out of 25 responses to fast onset and slow onset exacerbation scenarios. Potentially predictive factors measured included anxiety, depression, personality, optimism, perceived involvement in care and specific features of asthma.

Median scores for both scenarios were 12. Having a written asthma management plan, being female and having had a previous slow-onset attack were associated with adequate practical knowledge about the slow onset scenario.

Asthma Exacerbations And The Format Of Peak Flow Charts

Helen K Reddel, Stephen D.Vincent1, Jane Civitico2
1. Woolcock Institute of Medical Research (RPAH and University of Sydney), Camperdown NSW 2050,
2. Royal Prince Alfred Hospital Camperdown, NSW 2050

It seems that the format of peak flow charts, and particularly the horizontal scale on which the data are plotted, may have an important impact on the detection of exacerbations by patients and health care professionals.

There were striking differences in the appearance of the exacerbation when it was plotted in different formats.

The Impact of Asthma on Quality of Life

Rosario D. Ampon1,2, Margaret Williamson1,3, Leanne M. Poulos1 and Guy B. Marks1
1.Australian Centre for Asthma Monitoring (ACAM) Woolcock Institute of Medical Research,
2. Children’s Hospital at Westmead, 3School of Health Information Management, University of Sydney.

The aim of this study was to measure the impact of having asthma on three aspects of quality of life: psychological distress, self-perceived health and life satisfaction.

The study concluded that the presence of asthma is associated with poor quality of life and perceived health status and higher than average levels of psychological distress. These represent quantifiable impacts of asthma that can be monitored and, potentially, modified with improved approaches to asthma prevention and control.

Asthma Severity and the Impact on Quality of Life (QoL)

Patricia K Correll1, Margaret Williamson1,2 and Guy B Marks1
1. Australian Centre for Asthma Monitoring (ACAM) Woolcock Institute of Medical Research, NSW 2050.
2. School of Health Information Management, University of Sydney, NSW 2006

After adjusting for demographic factors, comorbidities and smoking, having moderate to severe asthma versus mild asthma was significantly associated with poorer perceived health (odds ratio 2.25 95% confidence interval 1.88-2.68) poorer functioning (OR 1.78 95%CI 1.31-2.44), greater psychological distress (OR 1.68 95%CI 1.40-2.01) and problems with mobility (OR 1.57 95%CI 1.22-2.03), performing usual activities (OR 1.59 95%CI 1.24-2.04), pain and discomfort (OR 1.29 95%CI 1.05-1.58) and anxiety and depression (OR 1.40 95%CI 1.22-1.74).

These results demonstrate that among people with asthma the presence of moderate to severe asthma is associated with a substantially increased risk of having reduced QoL, including level of physical and psychological functioning and perceived health status.

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Evidenced-Based Asthma Management In The Emergency Department (ED).

Jason Bower1, Susan A Welch1, Cassandra A Slader1,2.
1. Pharmacy Department, Therapeutics Centre, St Vincent's Hospital (SVH) Darlinghurst, 2010.
2. Faculty of Pharmacy, University of Sydney, 2006.

To date at St Vincent's Hospital Sydney, standardised guidelines for acute asthma management in the ED have not been developed. The National Asthma Council has recently updated its guidelines for the emergency management of asthma. Additional recommendations are suggested by analysis of the systematic reviews in the Cochrane Database. The aim of this study was to compare the current ED management of acute asthma with the evidenced-based guidelines, and to identify practice inconsistent with these guidelines.

Fourteen patients (23-77 years) were admitted during this period. Seven patients were classified as moderate severity acute asthma, seven as severe. Spirometry and peak expiratory flow were not measured in 79% (6/7 moderate, 5/7 severe) and 43% (5/7 moderate, 1/7 severe) of patients respectively. Initial oxygen flow-rate was suboptimal in 57% (5/7 moderate, 3/7 severe). Prescribing of intravenous corticosteroids deviated from guidelines (43%; over utilisation for moderate, underutilisation for severe) and also for ipratropium bromide (underutilised for 6/7 severe patients). Use of magnesium sulfate was in accordance with the guidelines. Metered-dose inhalers with spacers are currently not used in the SVH ED.

Several key areas have been identified as inconsistent with the evidenced-based guidelines utilised. These will be addressed in the subsequent guideline implementation and education phase.

Effect Of Fetal Gender On Maternal Asthma During Pregnancy

Philippa Talbot1, Vanessa Murphy1, Carolyn Kessell2, Warwick Giles1, Roger Smith1, Peter Gibson2 & Vicki Clifton1
1. Mothers and Babies Research Centre and
2. Respiratory and Sleep Medicine, Hunter Medical Research Institute, Newcastle, NSW 2310

The study suggests that the female fetus is associated with worsening maternal asthma during pregnancy relative to the male fetus.

Furthermore it highlights that asthma education and close monitoring of asthma during pregnancy are important aspects of obstetric care.

Enhancing Links Between Hospital And Community Based Services to Facilitate And Coordinate a Paediatric Asthma Management Program

Christine Burns1, Melinda Gray2 and Professor Richard Henry2
1. St George Hospital, Kogarah, NSW
2. Sydney Children’s Hospital Randwick, NSW

The “Aiming for Asthma Improvement in Children” program commenced in July 2001 in the South East Health area in Sydney. Through a service provision model that promotes evidence-based research, the facilitation and coordination of a paediatric asthma management and education program has been established. Implementation of standardised emergency department clinical practice guidelines, strengthening of links between the hospital and community, and delivery of asthma education and training to key target groups form the basis of the model. At local levels, liaising and coordinating with key stakeholders have been integral components in ensuring the sustainability and delivery of the service.

Paediatric asthma emergency department presentations and inpatient separations have shown a decrease of 13%(263), and 15%(175) respectively, compared to figures from the financial year of 2000/2001. A minimum of 70% of schools and 40% of childcare services have received asthma emergency training for their staff with asthma management strategies implemented within their environments. Over 160 asthma education sessions have been delivered to key stakeholders.

Asthma In Childhood and Lung Function Decline in Adulthood

Xuan W, Toelle BG, Ng K, Belousova E, Marks GB Woolcock Institute of Medical Research, University of Sydney, NSW 2050

Airway hyperresponsiveness (AHR) measured in childhood is a significant predictor for lower FEV1/FVC ratio in adulthood, independent of the ratio measured in childhood. However, the decline in FEV1/FVC ratio between age 18 and 30 years is the same in people with and without AHR in childhood.

Relation Between Change In Asthma Prevalence And Use Of Preventer Medications

De Meer G, Ng K, Toelle BG & Marks GB The Woolcock Institute of Medical Research

Between 1992 and 2002 childhood asthma symptoms as well as symptom severity decreased. This cannot be attributed to increased use of preventer treatment, since there was a simultaneous negative trend in preventer treatment, particularly among those with more frequent symptoms.

Risk Factors for Near Fatal Asthma In Children

PJ Lyell1,2, E Villanueva3, D Burton2, NJ Freezer1,4 and PG Bardin1,4
1. Department of Respiratory and Sleep Medicine; Monash Medical Centre.
2. Charles Sturt University.
3. Monash Institute of Health Services Research.
4. Monash University.

The asthmatics with near fatal asthma (NFA) were more likely to be male (p=0.05), older (p=0.01), have younger siblings (p=0.05) and a longer duration of asthma (p=0.02). They were also more likely to have hayfever (p=0.002), use inhaled corticosteroids (p=0.001), long acting β2 agonists (p=0.02), have an asthma management plan (p=0.006), see a respiratory specialist (p=0.001) and have poor adherence with medication (p=0.003).

Parental smoking showed no differences between the groups. Multivariate analysis identified male sex (p=0.05) and inhaled corticosteroids (p=0.07) as factors associated with NFA.

The study identifies a number of factors associated with NFA, many are similar to those found in adult patients. Asthma severity may explain some of the findings but the data also suggest that other independent risk factors may operate in children.

Access To Spirometry In Less Accessible And Remote Areas Of Australia

Leanne M Poulos1, Wei Xuan1, Rose D Ampon1, Margaret Williamson1,2, and Guy B Marks1
1. Australian Centre for Asthma Monitoring (ACAM) 
2. School of Health Information Management, University of Sydney, NSW 2006.

There was a significant downward trend in the claims for spirometry with increasing remoteness among people of all ages (p=0.0027).

In major cities of Australia there were 9.0 claims per 100 population per year compared to 1.3 claims per 100 population per year in very remote areas.

There was a similar trend observed among people aged 5 to 34 years (p=0.02). In this age group, the rate of claims decreased from 5.3 per 100 population per year in major cities to 0.56 per 100 population per year in very remote areas of Australia.

Strategies are needed to improve access to spirometry among persons with respiratory disease living in remote and less accessible areas of Australia.

For full program abstracts go to

TSANZ
(http://www.thoracic.org.au)

Top of pageConference Diary 2004

Submit brief conference/meeting details to the National Asthma Council for possible posting in our Conference Diary by email to nac@NationalAsthma.org.au.

International Pediatric Respiratory, Allergy and Immunology Congress.
Hong Kong Convention and Exhibition Centre
10-13 July 2004.
IPRAIC Hong Kong
(http://www.ipriac.org)

 

IPRAIC logo

 

National Medicines Symposium 2004
Quality Use of Medicines - Time for total integration
Brisbane Convention and Exhibition Centre
Brisbane, Australia
28-30 July, 2004

National Medicines Symposium 2004

National Medicines Symposium

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Created March 26, 2004. Updated January 29, 2008